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The body's largest artery, carrying oxygenated blood from the left ventricle to the entire systemic circulation.
Medically reviewed & updated
The aorta is the largest blood vessel in the body. It begins at the left ventricle and serves as the main highway delivering oxygen-rich blood to every organ and tissue through its many branches. Like all large arteries, its wall is built to withstand high pressure and has elastic properties that help smooth out the pulsatile flow generated by each heartbeat.
The aorta is divided into several segments. The ascending aorta rises from the left ventricle just above the aortic valve; the right and left coronary arteries arise from its base to supply the heart muscle itself. The aortic arch curves up and over to the left, giving off three major branches that supply the head, neck, and arms: the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery. The arch continues as the descending thoracic aorta, which runs down through the chest behind the heart, then passes through the diaphragm at about the T12 vertebral level to become the abdominal aorta. The abdominal aorta supplies the abdominal organs before ending around the L4 vertebra, where it splits into the right and left common iliac arteries that supply the pelvis and legs.
During ventricular contraction (systole), the elastic aortic wall stretches to accommodate the surge of ejected blood, then recoils during relaxation (diastole). This "Windkessel" effect maintains continuous forward flow and a steady arterial pressure between beats, protecting smaller downstream vessels.
Because it carries the body's entire systemic blood output, aortic disease can be life-threatening. An aortic aneurysm is an abnormal bulging and weakening of the wall that can rupture. An aortic dissection occurs when the inner wall layers tear and blood splits the wall apart, a surgical emergency. Atherosclerosis can also stiffen and narrow the aorta. This content is educational and not medical advice.