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HealthVetted

Eli Lilly

Pharma maker of Mounjaro and Zepbound (tirzepatide), plus diabetes and other medicines

https://www.lillydirect.com

Products from Eli Lilly

  1. Top pick
    1
    Editor's Choice

    Zepbound

    FDA-approved tirzepatide for weight loss

    • Most effective FDA-approved weight-loss medication to date, with up to about 22.5% average body-weight loss at the 15 mg dose in SURMOUNT-1
    • Demonstrated head-to-head superiority over Wegovy (20.2% vs 13.7%) in the SURMOUNT-5 NEJM trial
    • Convenient once-weekly injection with a flexible dosing window (can be taken up to 4 days late)
    FDA-approvedBrand-nameOnce-weekly injectionDual GIP / GLP-1Insurance eligible
    8.4/10
    Editorial score
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  2. 2
    Runner-up

    Mounjaro

    Tirzepatide for type 2 diabetes

    • Category-leading efficacy: in the SURPASS-2 head-to-head trial it beat injectable semaglutide on both A1C (about 2.3-percentage-point reduction at 15 mg) and weight (roughly 11 kg, about 12%)
    • Dual GIP/GLP-1 mechanism delivers strong blood-sugar control plus substantial weight loss as a benefit for people with type 2 diabetes
    • Convenient once-weekly injection with a pre-filled pen, no daily pills or daily dosing
    Off-label useOnce-weekly injectionDual GIP / GLP-1Insurance eligible
    8.3/10
    Editorial score
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  3. 3
    Also great

    Foundayo (orforglipron)

    The anytime, no-food-restriction GLP-1 pill

    • Only GLP-1 pill that can be taken any time of day with no food or water restrictions
    • First-in-class non-peptide small-molecule GLP-1, simplifying manufacturing and dosing
    • Phase 3 ATTAIN-1 results published in NEJM with meaningful weight loss and cardiometabolic improvements
    FDA-approvedBrand-nameDaily oral tabletInsurance eligible
    8.1/10
    Editorial score
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