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GLP-1 receptor agonist
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GLP-1 receptor agonist
| # | Product | Active ingredient | Starting price | FDA status | Score | |
|---|---|---|---|---|---|---|
| 1 | BetterHelp | — | $260/mo | service | Top ·7.9 | See offer → |
| 2 | Online-Therapy.com | — | Best ·$50/mo | service | 7.6 | See offer → |
BetterHelp is a digital platform, not a treatment itself. You complete an intake questionnaire, and an algorithm plus human review matches you with a licensed therapist (LCSW, LPC, LMFT, or psychologist), usually within a day or two. You then receive talk therapy through a weekly live session of roughly 30-45 minutes by video, phone, or live chat, plus the ability to message your therapist between sessions. The therapeutic work itself is standard psychotherapy (such as CBT-style approaches), just delivered remotely; you can switch therapists at any time at no extra cost if the fit isn't right.
Online-Therapy.com is a delivery platform built around cognitive behavioral therapy (CBT), one of the most evidence-based talk-therapy models. After you pick your areas of concern and get matched with a licensed therapist, you work through an eight-section online CBT course delivered as video, audio, and text. The program's "toolbox" reinforces the work: interactive worksheets your therapist reviews and responds to (per the company, replies come on weekdays, typically within about 24 hours), a daily journal, an activity-planning tool, progress tests, and yoga/meditation videos. You also get unlimited asynchronous messaging with your therapist, and depending on your plan, one or two 45-minute live sessions per week by video, voice, or text chat. The goal is to help you identify and reframe unhelpful thoughts and behaviors through continuous practice between sessions. The therapy itself is standard CBT, just delivered remotely.
A peer-reviewed naturalistic study of 318 BetterHelp users, published in JMIR mHealth and uHealth (2019), found depression symptom severity fell significantly over three months: mean PHQ-9 scores dropped from 12.57 (moderate) to 9.36 (mild), a statistically significant change (p < .001) with a medium effect size (Cohen's d = 0.61). About 37.8% showed clinically significant improvement and 19.8% reached remission. Important limitations: the study had no control group (so it cannot prove BetterHelp caused the improvement), and two of its authors disclosed ties to BetterHelp (a former consultant and a company employee), which is a conflict of interest to keep in mind. Separately, BetterHelp's own 2024 platform-outcomes white paper reports that 72% of clients experienced symptom reduction within 12 weeks, but as company-published, non-peer-reviewed data, that figure should be treated with caution. More broadly, multiple meta-analyses find remote (tele)therapy is generally comparable to in-person care for common conditions like anxiety and depression, though a few studies note a modest in-person advantage for depression.
Online-Therapy.com has not published independent peer-reviewed trials of its own program, so its efficacy case rests on the broad evidence base for guided internet-delivered CBT (iCBT), which closely mirrors its model rather than proving results for this specific platform. A 2020 systematic review and meta-analysis in the Journal of Medical Internet Research found large effects for iCBT in routine care: Hedges' g = 1.18 (95% CI 1.06-1.29) for depression and g = 0.94 (95% CI 0.83-1.06) for anxiety, with outcomes broadly comparable to face-to-face therapy and larger effects on depression when trained professionals provided the guidance (g = 1.27 vs 0.92; this professional advantage was not seen for anxiety). Deterioration rates were low (about 2.5 percent for depression and 3.1 percent for anxiety). These are category-level findings, not measurements of Online-Therapy.com. Reviewer-conducted user surveys (for example, HelpGuide's survey of 100 users) reported roughly 87 percent overall satisfaction, but satisfaction surveys are not clinical outcome measures and should be read as user sentiment, not proof of effectiveness.
Talk therapy is generally low-risk, but it is not side-effect-free: discussing painful topics can temporarily increase distress, anxiety, or emotional fatigue, and progress can feel slow or stall. Platform-specific drawbacks include inconsistent therapist quality, occasional matching mismatches that require a switch, and limited usefulness in emergencies, since BetterHelp is not a crisis service. The most serious historical concern is privacy: in 2023 the FTC charged BetterHelp with sharing sensitive user data (including health-questionnaire responses, email addresses, and IP data) with advertisers such as Facebook, Snapchat, Criteo, and Pinterest, despite promising to keep that data private. BetterHelp agreed to pay $7.8 million (used for partial consumer refunds) and is now barred from sharing such data for advertising.
As talk therapy, Online-Therapy.com has no pharmacological side effects. The most common downside is temporary emotional discomfort when working through difficult thoughts or memories, which is a normal part of CBT. Research on guided iCBT shows low symptom-deterioration rates (roughly 2.5-3 percent), but a minority of people do not improve or feel worse, especially if the modality or therapist fit is poor. Because the platform cannot prescribe medication or provide real-time crisis intervention, the main risk is relying on it for conditions it is not designed to treat. Anyone experiencing worsening symptoms, suicidal thoughts, or a crisis should seek in-person or emergency care immediately and contact 988 or 911.
As of 2026, BetterHelp typically costs about $70-$100 per week, which works out to roughly $280-$400 per month; exact pricing varies by location and therapist availability, and the company has been rolling out weekly billing across most of the US. Need-based financial aid can reduce the rate for those who qualify. Historically BetterHelp did not accept insurance, but as of early 2026 it has begun adding coverage through select insurers (such as Cigna, UnitedHealthcare, Aetna, and Optum) in a limited number of states. With strong insurance, traditional in-network therapy (often a $15-$40 copay per visit) can be cheaper; without insurance, BetterHelp's flat rate may undercut typical $100-$200 self-pay session fees.
As of 2026, Online-Therapy.com is self-pay with three individual tiers billed monthly: Basic about $60/week (roughly $260/month), Standard about $90/week (roughly $390/month), and Premium about $120/week (roughly $520/month); a Couples plan is also offered. New users typically get 20 percent off the first month. It does not accept insurance and is not in-network, but it does accept HSA/FSA cards (your card issuer can still approve or decline the charge), and it provides itemized receipts you can submit to your insurer to seek possible out-of-network reimbursement. Pricing can change with promotions, so confirm current rates at checkout.
Best for adults with mild-to-moderate anxiety, depression, stress, relationship issues, grief, or life transitions, and for people facing practical barriers to in-person care (rural location, mobility limits, tight schedules). It is NOT appropriate for psychiatric emergencies, active suicidal thoughts, psychosis, severe eating disorders, or substance-use crises. BetterHelp therapists do not prescribe medication, do not provide formal diagnoses for legal or disability purposes, and do not fulfill court-ordered therapy. Anyone in crisis should call or text 988 (Suicide and Crisis Lifeline) or call 911. People who need medication management require a separate prescriber or psychiatry service.
Best for adults (18+) with mild-to-moderate anxiety, depression, stress, low self-esteem, or relationship issues who are self-motivated and comfortable with a homework-driven CBT format and a digital-first relationship with their therapist. A separate Couples plan exists. It is the wrong choice if you need psychiatric medication (the platform does not prescribe), have a severe or unstable condition, experience active suicidal thoughts, psychosis, mania, or substance-use emergencies, or want to bill in-network insurance. Minors and anyone in crisis should not use it. In an emergency, call 911 or call or text the 988 Suicide and Crisis Lifeline.
Online-Therapy.com: Online-Therapy.com is a legitimate, self-pay platform built around cognitive behavioral therapy (CBT): it pairs you with a state-licensed therapist and a structured digital toolbox (an eight-section CBT course, worksheets, journal, activity plan, tests, and yoga/meditation videos) plus unlimited messaging and, depending on plan, one or two 45-minute live sessions a week. Plans run about $60/$90/$120 per week (billed monthly) as of 2026. It suits motivated adults with mild-to-moderate anxiety, depression, or stress, but it cannot prescribe medication, does not bill insurance, and is not built for crises or severe conditions. Both are strong options — match the pick to your specific needs, budget, and clinician's guidance.
Editorial comparison, not medical advice. Discuss options with a qualified clinician. Individual results vary.