DisclosureWe earn commission on partner links; ranking is set by our evidence-based methodology — not advertisers. Read policy

Photo: HealthVetted editorial render
GLP-1 receptor agonist

Photo: HealthVetted editorial render
GLP-1 receptor agonist
| # | Product | Active ingredient | Starting price | FDA status | Score | |
|---|---|---|---|---|---|---|
| 1 | Talkiatry | — | Best ·— | service | Top ·8.1 | See offer → |
| 2 | BetterHelp | — | $260/mo | service | 7.9 | See offer → |
Talkiatry is a telehealth psychiatry practice, not a medication or device. You complete an online intake about your symptoms, history, and insurance; the platform verifies your coverage and matches you to a licensed, board-certified psychiatrist. You then meet by video for a comprehensive initial evaluation (typically 60-90 minutes), receive a diagnosis and treatment plan, and have shorter follow-up visits for medication management and adjustment. Prescriptions are sent electronically to your pharmacy, and the same psychiatrist provides continuity of care. Therapy is added through your psychiatrist or a Talkiatry therapist referral rather than booked as a standalone service.
BetterHelp is a digital platform, not a treatment itself. You complete an intake questionnaire, and an algorithm plus human review matches you with a licensed therapist (LCSW, LPC, LMFT, or psychologist), usually within a day or two. You then receive talk therapy through a weekly live session of roughly 30-45 minutes by video, phone, or live chat, plus the ability to message your therapist between sessions. The therapeutic work itself is standard psychotherapy (such as CBT-style approaches), just delivered remotely; you can switch therapists at any time at no extra cost if the fit isn't right.
Talkiatry has not published independent randomized clinical trials of its platform, so its effectiveness is best judged by the model rather than trial data: care is delivered by board-certified psychiatrists using standard, evidence-based psychiatric treatment, and the broader research literature shows telepsychiatry is generally comparable to in-person care for diagnosis and medication management of common conditions like depression and anxiety, with in-person evaluation preferred for higher-acuity or closely monitored cases. Independent reviewers report favorable user-survey results: in HelpGuide's user survey, 90% of surveyed Talkiatry users said they would recommend the service and most reported being satisfied or very satisfied with their care; these are self-reported satisfaction figures, not clinical outcome measures. The most consistent real-world benefit is access: appointments within roughly 1-2 weeks versus traditional psychiatry waits that can stretch 3-6 months in many areas.
A peer-reviewed naturalistic study of 318 BetterHelp users, published in JMIR mHealth and uHealth (2019), found depression symptom severity fell significantly over three months: mean PHQ-9 scores dropped from 12.57 (moderate) to 9.36 (mild), a statistically significant change (p < .001) with a medium effect size (Cohen's d = 0.61). About 37.8% showed clinically significant improvement and 19.8% reached remission. Important limitations: the study had no control group (so it cannot prove BetterHelp caused the improvement), and two of its authors disclosed ties to BetterHelp (a former consultant and a company employee), which is a conflict of interest to keep in mind. Separately, BetterHelp's own 2024 platform-outcomes white paper reports that 72% of clients experienced symptom reduction within 12 weeks, but as company-published, non-peer-reviewed data, that figure should be treated with caution. More broadly, multiple meta-analyses find remote (tele)therapy is generally comparable to in-person care for common conditions like anxiety and depression, though a few studies note a modest in-person advantage for depression.
Talkiatry itself is a service, so the medical risks come from the medications its psychiatrists may prescribe. Antidepressants (SSRIs/SNRIs) can cause nausea, insomnia, and sexual side effects, and carry an FDA boxed warning for increased suicidal thoughts and behavior in patients under 25. Stimulants for ADHD can raise heart rate and blood pressure, reduce appetite, disturb sleep, and carry abuse and dependence potential. Mood stabilizers and antipsychotics have their own monitoring needs, sometimes including lab work. Because care is virtual, a limitation is that some conditions ideally warrant in-person evaluation or vital-sign and lab monitoring. Report any new or worsening symptoms to your prescriber, and never rely on Talkiatry for emergencies or suicidal crises (call or text 988, or call 911).
Talk therapy is generally low-risk, but it is not side-effect-free: discussing painful topics can temporarily increase distress, anxiety, or emotional fatigue, and progress can feel slow or stall. Platform-specific drawbacks include inconsistent therapist quality, occasional matching mismatches that require a switch, and limited usefulness in emergencies, since BetterHelp is not a crisis service. The most serious historical concern is privacy: in 2023 the FTC charged BetterHelp with sharing sensitive user data (including health-questionnaire responses, email addresses, and IP data) with advertisers such as Facebook, Snapchat, Criteo, and Pinterest, despite promising to keep that data private. BetterHelp agreed to pay $7.8 million (used for partial consumer refunds) and is now barred from sharing such data for advertising.
As of 2026, Talkiatry is insurance-based with no cash self-pay option. With accepted insurance, the majority of visits cost patients $30 or less out of pocket; depending on your plan, copays or coinsurance commonly run roughly $15-$30 but can be higher (for example $50-$100 or more) before a deductible is met, and the longer initial evaluation may cost more than follow-ups. Talkiatry verifies in-network status before your first appointment and states that if it makes a verification error, it will cover the full cost of that first visit. It does not accept Medicaid; it does accept Original Medicare Part B and select Medicare Advantage plans (coverage varies by state). If your insurance is not accepted, you cannot use Talkiatry, because no out-of-network or self-pay rate is offered.
As of 2026, BetterHelp typically costs about $70-$100 per week, which works out to roughly $280-$400 per month; exact pricing varies by location and therapist availability, and the company has been rolling out weekly billing across most of the US. Need-based financial aid can reduce the rate for those who qualify. Historically BetterHelp did not accept insurance, but as of early 2026 it has begun adding coverage through select insurers (such as Cigna, UnitedHealthcare, Aetna, and Optum) in a limited number of states. With strong insurance, traditional in-network therapy (often a $15-$40 copay per visit) can be cheaper; without insurance, BetterHelp's flat rate may undercut typical $100-$200 self-pay session fees.
For: insured adults and children age 5 and older with conditions such as depression, anxiety, ADHD, bipolar disorder, OCD, PTSD, or insomnia who want diagnosis and ongoing medication management from a psychiatrist. Requires accepted commercial insurance (for example Aetna, Cigna, UnitedHealthcare/Optum, Blue Cross Blue Shield, and others) or Original Medicare Part B / select Medicare Advantage plans, and residence in a covered state (roughly 43 states as of 2026; accepted plans vary by state). Not for: people who are uninsured or want to pay cash (there is no self-pay option), Medicaid members, those in non-covered states, anyone in crisis or needing emergency, inpatient, or higher-level care, and people seeking standalone talk therapy or treatment for conditions such as severe eating disorders that need in-person care.
Best for adults with mild-to-moderate anxiety, depression, stress, relationship issues, grief, or life transitions, and for people facing practical barriers to in-person care (rural location, mobility limits, tight schedules). It is NOT appropriate for psychiatric emergencies, active suicidal thoughts, psychosis, severe eating disorders, or substance-use crises. BetterHelp therapists do not prescribe medication, do not provide formal diagnoses for legal or disability purposes, and do not fulfill court-ordered therapy. Anyone in crisis should call or text 988 (Suicide and Crisis Lifeline) or call 911. People who need medication management require a separate prescriber or psychiatry service.
BetterHelp: BetterHelp is a subscription online-therapy platform that pairs you with a licensed therapist for weekly video, phone, or chat sessions plus between-session messaging, costing roughly $280-$400 per month as of 2026. Peer-reviewed data suggest meaningful relief of depression symptoms, but it offers no medication, isn't built for severe illness or crises, and carries a notable privacy history including a 2023 FTC settlement. Both are strong options — match the pick to your specific needs, budget, and clinician's guidance.
Editorial comparison, not medical advice. Discuss options with a qualified clinician. Individual results vary.