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Photo: HealthVetted editorial render
GLP-1 receptor agonist

Photo: HealthVetted editorial render
GLP-1 receptor agonist
| # | Product | Active ingredient | Starting price | FDA status | Score | |
|---|---|---|---|---|---|---|
| 1 | Transparent Labs Fat Burner Stim-Free | — | $69/mo | supplement | Top ·6.9 | See offer → |
| 2 | Leanbean | — | Best ·$60/mo | supplement | 5.5 | See offer → |
It combines four plant-derived compounds that may nudge metabolism and appetite without stimulants. Green tea catechins (EGCG) and Capsimax (capsaicin) have been shown to modestly raise energy expenditure and fat oxidation; Paradoxine (grains of paradise, standardized to 6-paradol) is thought to activate brown adipose tissue to burn calories as heat; ForsLean (Coleus forskohlii, standardized to forskolin) raises cyclic AMP, which is linked to fat mobilization. Capsaicin and grains of paradise may also blunt appetite, which can make a calorie deficit easier to maintain. The formula contains no caffeine or other stimulants.
Glucomannan is a soluble fiber from the konjac root that absorbs many times its weight in water and forms a viscous gel in the stomach. Taken before meals with water, it expands and promotes a sense of fullness, which can reduce how much you eat. Chromium is added for blood-sugar support and B-vitamins for normal energy metabolism. The trace green coffee provides negligible stimulation, keeping the experience gentle.
No trial tests this exact blend, so evidence comes from each ingredient and several of the studies are small. A 2005 Obesity Research study (Godard et al.) found 250 mg of 10% forskolin twice daily for 12 weeks significantly reduced body fat percentage and fat mass in 15 overweight and obese men, though total body weight did not differ from placebo. A 2014 trial in the Journal of Nutritional Science and Vitaminology found 30 mg/day of grains of paradise extract increased whole-body energy expenditure and reduced visceral fat versus placebo in a small group of women. Capsaicin and green tea catechins have been shown to modestly raise energy expenditure and fat oxidation, but a 2010 American Journal of Clinical Nutrition meta-analysis put green tea's weight effect at roughly 1 kg or less, which the authors call clinically modest at best. Net: real but small, deficit-dependent effects.
Glucomannan at around 3 g/day is the dose tied to an EFSA-recognized claim for weight reduction in a calorie-restricted diet, and several randomized trials and reviews show small, real reductions in body weight when used as a pre-meal preload. However, systematic reviews (e.g. Zalewski et al., 2015) found the effect inconsistent and modest, and NIH notes limited long-term, high-quality data. The non-fiber ingredients contribute little independent weight-loss evidence.
Because it has no stimulants, most users report no jitters, anxiety, or sleep disruption. The most common complaint is mild gastrointestinal upset, nausea, warmth, or a "hot" sensation from the Capsimax and Paradoxine pepper extracts, especially on an empty stomach; taking the capsules with food and water tends to reduce this. Rare but more serious concerns relate to the ingredients themselves: high-dose green tea extract has been associated with uncommon, idiosyncratic cases of liver injury (documented in the NIH LiverTox database), and forskolin can lower blood pressure and may interact with anticoagulants and antihypertensives. Stop use and seek medical care if you notice yellowing skin or eyes, dark urine, severe abdominal pain, or signs of very low blood pressure such as dizziness or fainting.
Because the active ingredient is bulking fiber, the most common effects are bloating, gas, and looser stools, which often ease over time. The most important safety point: always take glucomannan with a full glass of water and never dry, as it can swell in the throat or esophagus and pose a choking or blockage risk. This is educational information, not medical advice.
As of 2026, Transparent Labs lists this product at about $54.99, often discounted to around $49.99, for a 120-capsule bottle that delivers 60 servings, or roughly a 30-day supply at the full 4-capsule daily dose. That works out to about $0.83-$0.92 per 2-capsule serving, or roughly $1.65-$1.83 per day. Third-party retailers sometimes price it lower (around $45) or higher. Subscribe-and-save and periodic sitewide promo codes can trim the price further. As a dietary supplement it is paid out of pocket and is generally not covered by insurance, and typically not HSA/FSA eligible without a documented medical need. It is occasionally out of stock or branded as "Body Recomp," so verify you are buying the stim-free version.
As of May 2026, a one-month supply is about $59.99 on the official site, with multi-month bundles lowering the monthly cost. There is no insurance coverage. A 90-day money-back guarantee is advertised. Note that generic glucomannan supplements deliver the same key fiber for a fraction of the price.
Best for adults who want appetite and metabolic support but are caffeine-sensitive, train in the evening, or already use a separate stimulant pre-workout, and who already have a genuine diet and exercise plan and want a marginal edge. Avoid it if you are pregnant, breastfeeding, or under 18; if you take blood pressure, blood thinner, or diabetes medications (forskolin can lower blood pressure and may interact with anticoagulants and antihypertensives, and green tea can affect some drugs); if you have liver disease (high-dose green tea extract has rare liver-injury reports); or if you have an active ulcer or significant reflux, since the pepper and ginger-family extracts can irritate the gut. This is general information, not medical advice; check with your doctor before starting any supplement.
Marketed to adult women seeking appetite support, though the mechanism applies to anyone. Not for those under 18 or who are pregnant or breastfeeding without clinician approval. People with swallowing difficulties, esophageal narrowing, or who take oral medications (timing matters, as fiber can affect absorption) should consult a clinician first.
Leanbean: Leanbean is a low-stimulant, fiber-forward appetite-support supplement whose star ingredient (3 g glucomannan) has genuine but modest evidence; the formula is honest and gentle, but you pay a premium for what is largely fiber plus vitamins. On balance, Transparent Labs Fat Burner Stim-Free edges ahead in our scoring, but the right choice depends on your situation.
Editorial comparison, not medical advice. Discuss options with a qualified clinician. Individual results vary.