Hims Testosterone Support review: is it worth it?
Hims offers OTC testosterone-support gummies plus a telehealth path to clinician-supervised therapy if labs warrant it.
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A fertility-friendly testosterone option, with real regulatory caveats
Hims Testosterone Support is genuinely different from a drugstore "test booster": its active ingredient, enclomiphene, is a prescription SERM with solid clinical data showing it normalizes testosterone in men with secondary hypogonadism while keeping sperm production intact. The major caveats are that enclomiphene is not FDA-approved and is dispensed as a compounded medication, and Hims requires you to prepay for a 3-, 5-, or 10-month plan. It can be a reasonable, convenient choice for the right candidate working with a clinician, but it is not for everyone, and the decision belongs with you and a prescriber who knows your health history.
Check PriceFrom $30/mo
Pros
- ✓Active ingredient enclomiphene has real randomized-trial evidence for normalizing testosterone in secondary hypogonadism (about +274 ng/dL versus placebo in a 2025 meta-analysis), not just a generic herbal 'booster'
- ✓Preserves fertility and sperm production, unlike injected or topical testosterone, making it attractive for younger men or those who want children
- ✓All-in-one telehealth model bundles the prescription, provider check-ins, lab monitoring, and discreet shipping into one subscription
- ✓Oral daily pill avoids the injections, gels, and transfer risks of conventional testosterone replacement therapy
- ✓Optional add-ons (supporting nutrients and, if eligible, tadalafil for erections) let the plan be tailored to individual goals
Cons
- ✕Enclomiphene is NOT FDA-approved (its Androxal application received an FDA Complete Response Letter in 2015 and development was discontinued in 2021) and is dispensed as a compounded drug whose quality and consistency the FDA does not verify
- ✕You must prepay for a 3-, 5-, or 10-month plan upfront, and these prescription charges are generally non-refundable even if it doesn't work for you
- ✕Almost never covered by insurance, so it's an ongoing out-of-pocket cost; generic clomiphene or FDA-approved TRT can be cheaper elsewhere
- ✕Long-term safety data specific to enclomiphene is limited (meta-analysis safety endpoints were underpowered), and it only helps secondary hypogonadism, not testicular failure or normal-testosterone fatigue
- ✕Care is virtual and tied to the Hims platform, which is less hands-on than an in-person endocrinologist or urologist for a hormone condition
How it works
The active ingredient is enclomiphene, a selective estrogen receptor modulator (SERM). It blocks estrogen receptors in the hypothalamus and pituitary, which the brain interprets as "estrogen is low." In response, the pituitary releases more luteinizing hormone (LH) and follicle-stimulating hormone (FSH), signaling the testicles to produce more of their own testosterone and to keep making sperm. This is fundamentally different from traditional testosterone replacement therapy (TRT), which adds testosterone from outside the body and can shut down the body's own production and reduce sperm counts. Hims sometimes bundles enclomiphene with supporting nutrients (such as zinc and B-vitamins) and, for eligible men, tadalafil for erectile function, but enclomiphene is the workhorse of the formula.
Effectiveness
Enclomiphene has a credible clinical track record for secondary hypogonadism. In a 2014 randomized Phase II trial published in Fertility and Sterility (124 men with morning testosterone below 250 ng/dL), enclomiphene at 12.5 mg and 25 mg raised morning testosterone, LH, and FSH to levels comparable with 1% topical testosterone gel, while conserving sperm counts. A 2025 systematic review and meta-analysis of 10 randomized trials (819 men) found SERM therapy increased total testosterone by a mean of about 274 ng/dL versus placebo (95% CI ~192-356 ng/dL), with LH up ~4.7 IU/L and FSH up ~4.6 IU/L, and no significant difference in testosterone versus testosterone gel. Crucially, unlike testosterone gel (which in Phase III data reduced sperm density by roughly 33-57%), enclomiphene caused only minimal change in sperm density (about 12-15%), preserving fertility. Important caveat: despite this data, enclomiphene's new-drug application (Androxal) received an FDA Complete Response Letter in December 2015 requesting additional Phase 3 work, and development was discontinued for all indications in 2021, so it is not an FDA-approved drug.
Side effects
Commonly reported side effects of enclomiphene include headache, hot flashes, mood changes, nausea, and breast tenderness or sensitivity. Because it works partly by raising estradiol as well as testosterone, some men notice estrogen-related effects. If tadalafil is added, expect possible headache, flushing, indigestion, back or muscle pain, and nasal congestion. Less common but more serious concerns reported with SERMs in this class include visual disturbances (blurring or floaters) and blood-clot risk; vision changes warrant stopping the drug and contacting a clinician. Long-term safety data specific to enclomiphene is limited, and the 2025 meta-analysis explicitly noted its safety endpoints were underpowered, so ongoing monitoring matters. Seek urgent care for chest pain, a sudden vision change, signs of a clot (leg swelling or pain, shortness of breath), or an erection lasting over four hours.
Cost
Starts at $30/mo from Hims.
As of 2026, Hims prices its testosterone program by plan length, paid upfront: roughly $199/month on a 3-month plan, about $139/month on a 5-month plan, and around $99/month on a 10-month plan, which bundles medication, provider check-ins, lab monitoring, and shipping. You typically prepay for the full 3-, 5-, or 10-month term, and these prescription-program charges are generally not refundable. Because enclomiphene is compounded and not FDA-approved, it is essentially never covered by insurance, so expect to pay out of pocket; some men find generic clomiphene or, where appropriate, FDA-approved TRT cheaper through a local prescriber and pharmacy. Lab fees and any office visits outside the bundle can add to the total, and prices change frequently, so confirm current figures directly with Hims.
Is it worth it?
If you have lab-confirmed low testosterone of the secondary (pituitary-signaling) type and want to protect fertility, Hims' enclomiphene-based program is evidence-backed and easy to access online. Just go in clear-eyed: the drug isn't FDA-approved, it's compounded, you pay months in advance and prescription charges are generally non-refundable, and long-term safety data is limited. Confirm low testosterone with bloodwork and discuss alternatives like FDA-approved TRT or generic clomiphene with your own doctor before starting, switching, or stopping any hormone therapy.
Frequently asked questions
Is Hims testosterone support FDA-approved?
No. The main ingredient, enclomiphene, is not FDA-approved; its new-drug application (Androxal) received an FDA Complete Response Letter in December 2015 asking for more Phase 3 data, and development was discontinued for all uses in 2021. Hims dispenses enclomiphene as a compounded medication, which the FDA does not review for safety, effectiveness, or quality.
Does Hims testosterone (enclomiphene) actually work?
For men with secondary hypogonadism, the evidence is reasonably strong. Randomized trials and a 2025 meta-analysis of 10 trials (819 men) show enclomiphene and related SERMs raise total testosterone by roughly 274 ng/dL versus placebo, to levels comparable with testosterone gel, while preserving sperm production. Individual results vary and depend on a clinician's dosing and monitoring.
How is enclomiphene different from TRT?
TRT adds testosterone from outside the body, which can shut down natural production and reduce sperm counts. Enclomiphene instead signals your own testicles to make more testosterone and keeps fertility intact, making it a better fit for men who may want children. Enclomiphene is also not FDA-approved, whereas several TRT products are.
How much does Hims testosterone cost in 2026?
As of 2026, plans run about $99-$199 per month depending on length, paid upfront: roughly $199/month for a 3-month plan, $139/month for 5 months, and $99/month for 10 months. The price bundles medication, lab monitoring, and provider check-ins, but it's generally non-refundable and not covered by insurance. Confirm current pricing directly with Hims.
Will enclomiphene affect my fertility or sperm count?
Enclomiphene is specifically chosen to preserve fertility. In Phase III data it caused only minimal change in sperm density (about 12-15%), while testosterone gel reduced it by roughly 33-57%, which is why it appeals to men who want to raise testosterone without compromising the ability to conceive. If you are actively trying to conceive, discuss timing and monitoring with your prescriber.
What are the side effects of Hims testosterone support?
Common side effects include headache, hot flashes, mood changes, nausea, and breast tenderness. Less common but serious concerns include visual disturbances and blood-clot risk; stop and contact a clinician if you notice blurred vision or floaters, and seek urgent care for chest pain or leg swelling. Long-term safety data on enclomiphene is limited.
Who should not take Hims enclomiphene?
It's not for men with primary (testicular) hypogonadism, those with normal testosterone seeking a 'boost,' or anyone with a hormone-sensitive cancer or significant heart, liver, or vision conditions. Women and anyone who may become pregnant must not take it. A baseline blood test and provider review are required before it can be prescribed.
Do I need a blood test to get Hims testosterone treatment?
Yes. Hims requires a baseline testosterone test and a licensed provider's review of your health history before prescribing, plus ongoing lab monitoring to titrate the dose. It is a prescription program, not an instant over-the-counter purchase.
Is Hims testosterone support better than over-the-counter testosterone boosters?
They're not comparable. OTC 'boosters' (zinc, ashwagandha, fenugreek) have weak evidence and won't fix clinically low testosterone. Hims' program centers on prescription enclomiphene, which has genuine clinical trial data showing it raises testosterone, though it is compounded and not FDA-approved.
Sources
- Enclomiphene citrate stimulates testosterone production while preventing oligospermia: a randomized phase II clinical trial comparing topical testosterone — Fertility and Sterility (PubMed) (2014)
- Clomiphene or enclomiphene citrate for the treatment of male hypogonadism: a systematic review and meta-analysis of randomized controlled trials — Archives of Endocrinology and Metabolism (PMC / NLM) (2025)
- Enclomiphene Citrate for the Treatment of Secondary Male Hypogonadism — PMC / National Library of Medicine (2016)
- Androxal (enclomiphene): What is it and is it FDA approved? — Drugs.com (2025)
- Clomiphene and enclomiphene: Drugs, not dietary supplements — Operation Supplement Safety (U.S. Dept. of Defense) (2024)